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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f5efe942e9a0ac394f91d2a1bed90042b8f3ea1eb8f75981cfe1dbca8280e0' 
  AND token = 'j1pLP+MN8y6A8f7tQiXU5H9nhrQtsuX39WaKzyQDAWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}