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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '059557afef74dbe36a1dd3941a46792af5cb0716c5625372b90aa06a94543e4a' 
  AND token = 'edmtgKXr66MCv7BWGGDEzYA9mz+u0FydqH/cJlB+W9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}