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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e79d3ccb09921414b0adf594f249d2fbb17a743997418be4bd0a9c29f2c3f8' 
  AND token = 'Tr6ET1wOcKEKOdLWoa+Mdo7QT6qGEHwO9y3jScbpJ84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}