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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c43f0b6cfcbc8e697bd253e68055c18a5855ac657e8a4162e04c4c8aed7f7e16' 
  AND token = 'n6xfzH6xVJz7mKc0AxRxeu9YWyCY4NEt38YKDpt6L6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}