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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6882d51ba39be3304a47b496c38844f347aca4aade7ec1c4cc2d6d367ac57f0c' 
  AND token = 'uEeGDE1FUT8ijTpn6Upp6RbJ4+YL4jzD5MVKUbkgOSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}