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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b3536b9b2c8b11347510e24a38dbee3be09694dae2af58c8f1f3dad4465220e' 
  AND token = 'VFKiGxhLwFbJYR8PExrwX4kbrTBhT3EIXPoeuXcxM1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}