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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b274774fd4a129d5b825894c6cafd266ec0f013ff8ae58f8c518759ebbe97c' 
  AND token = 'vhNJoGyz+As2pzW4W+2jkl8TS74pTg/AF4TM4yyRjl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}