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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc240f22e47e6d03504b9b6002021f56f01c42aa29dfc548035b3890a26d3b3' 
  AND token = '+ehTAJSijjBZo1FsRQm+3oGAGuGsGVlFyq1jOVCq0q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}