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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18dd6886beda8ffef4b7a977764059694dc873f107b0035dc146716b5c7991b1' 
  AND token = 'WWXNy+l+38SI59I8EHznUL7G2hKH4lZkfXGaznS9ZF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}