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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3275213dfc5a479e7b7bfeb9ccd40748fa7d80fc0f9b876cb65001d06dd4c060' 
  AND token = '7lg3tYPUsMT2TeNxo2iE3zM8wA6aoWhF38LyWIFL+Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}