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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd09396a1c91a21dfad706f0b1e7744d3375353e1f721c2f23ddec6a3d67adefe' 
  AND token = 'l65NAyEsF1hHwNteoBx7oHy2lkNKH7ZOjEx7G6qFk8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}