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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7a3822d95497732dc6756913e5bd65a81689e18754c1e31710d791f58ba1a0b' 
  AND token = 'R3XL74f7vRNmACL/PT3xJcsPpjS7Mub90+QOkr3UFq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}