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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fdd28249ef67302ab0bc06a903a2c2f37c8b723d26410b4602071289a2ccfe8' 
  AND token = 'i49U4SNgOHmIfsQzeEnuIeq1G0cMfU6r9/JDjXU/9/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}