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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e80c845990102a7c88002bfcac14e680b831d699349ab72330638fd7eb62e75' 
  AND token = 'a3uYtT0RWN5mGkx77QyyMQ0UgOa9V0Sk17X6GMVc6vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}