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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ff9d53b6dcd1d6d1d8d294bec45312c1dbbbe341e8ed036a7a2a31c52912679' 
  AND token = 'T/BMyQfK9+GhboOzjLWXuzr3hc6WdMx+fbihlkM3pdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}