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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6081b548a9bce816c67f54a69f80cdb7ea3ab90d35b7d41174f0c7297a61e7ea' 
  AND token = 'nEJmaHdO8s967JVHaBfwiwp6X2GsMmnIEUx/r06YUZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}