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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b118a41749bb2720a5da5850a6ec0e3f3e9a982ffea7ac3570d29ab76f45deb3' 
  AND token = 'gw4bniC62cwDAqWoUp2rQALxTM6SE0bvohWmEKaU4YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}