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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b045a4222631512e2aa1e15bf3f73a40af40c1c4e5f0990cede10f3340645b3' 
  AND token = 'bpuRB19YcFFqMkrfOE/eA1UH6hzq9dq+PF1MfNzyac0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}