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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '742fa0067387175af75973bdcbc8363fbe1e3fbc7b1595229c30524ce3e1dc8e' 
  AND token = 'n9RuFUYe3uITiXXDEa9x9TRi7l3CHP07hdMC9nTkqog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}