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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd620ab8bfa062da175996370f1adb73b1a552beaa9a2c91a2f33ee404abfe097' 
  AND token = 'm4mjmqZqWjFlXysyXw+isAQ8var4Ls4TAmxbR5Xb30Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}