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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8cad25b825a9a1ddea8880baa1d8a6900cd810532c5e5c242c90d10c357c3d' 
  AND token = 'vvN0ugtrHFVfOycxhsWfdZn652t3mrFzteRC7Zt5P0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}