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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980e492b4b5cd996a43d92e00b436a83c9305f8edac04a7d76817a328dcb4654' 
  AND token = 'OOwUz4rkO9BgkfOa7b+8OguIZ+XR345ZrodJcoJm43g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}