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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7700e7dd4de598c7e67355c0e7e6f04624e07fcf5cb0f5d08751b149aa0d01ea' 
  AND token = 'UWNQqab0FDXEkAbHUl6z0tc49yUHyPjrL3T5RrS9pEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}