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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053eda2d0ce3849429471a68cb40a21726904e408e125d24ec277d5b30e66bf1' 
  AND token = '+/vflWOyxhRdfKr6lKa24DCfM4nPcDPP0YG/PPbI7ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}