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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f208cde2d1ee2d665a14ecd747bfdc83429214eafad8d49bf46ed3aacb5178a' 
  AND token = 'p/G+GTv4nVEar6y05qL61xDeH/4t17wsv9J+/XkYvo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}