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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a7eabe7e56bf9de3b1f8f589b78c5497f6e53f1f2017065b21f71b87ab2b7d' 
  AND token = '6ZmoRXNviZ33rol0If2+I9/t1nBJhGHm908ReRuCuaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}