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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d89aeb15b0d00a3ced84de84b15364b764e58aa6e1fc80b6c25e881374d0104' 
  AND token = 'hdIrf8VdNrTQv0+XRzKNcc3cT8qVjX/WeuGcpWSCOl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}