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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0214ae11510721f10964d5e4f0cf739677af85a6cc405ab4d2ef52ec11eccf59' 
  AND token = 'HhGL/xBryN40MgZqrrOfSRxF+CNMZvKBnxXrhU5B27A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}