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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e01546737660ef10e574919731a7320e74432bd53f328aad51a0d6c35ecf4d' 
  AND token = 's+afO49XF5pv3RBob5O6+ZklKEYdATDQRdIKjv7XfI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}