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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8394268b6593b1e8e56603977d41313a0d0ec6fdb2144ac23f3542ba63f9b111' 
  AND token = 'Z5H/bHdV7w3eQ0HzZ1SMpYNtT6SJi6v09LlTRl99qlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}