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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '720f9d35e3e02ac480af15c5fa2268c64a4999285e077e131b2275bb8781fbf1' 
  AND token = 'na3WdFO8OYhqaADTutME9IfDAgK9a2kwVkvz2lPwhaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}