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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f94d4483d08dde8131284a064d05221708f7d7cbd9276daa3c37da4419ff508' 
  AND token = 'QDeBZs/8zRv/2Mp6pJ1IARC78ps7YWHOUPIrQbe4yeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}