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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '941603d8dd8af628ff58c96697faf5ec08065bcfd8d65e03c8f036db767b6531' 
  AND token = 'IAmQY1QsLEvK2g9c0RamurBAenrnUJsibQzJ0NmS5rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}