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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fca5e2713cb3fc1590d980a0b8f20918e3dcea8708f025891e7a3edda95eb1f' 
  AND token = 'RBBTvBUxER4la0iJWKZQug/B1nOt25sgGIJI4kolHk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}