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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1dceeee4fec55f696af7ea6aaf2d309e77fa3b6020d50466c2130eb023bf04' 
  AND token = 'HdGSktEYD4g1i8/y99p52G0VoNk6EUJRw9+wLE5UeIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}