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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6c301642c47f0d2c6bdb7fbcbaa059dd2043b57f254dfae25300deedd2d92ea' 
  AND token = '2bFD+bJwdx+v+AQUPxAoVVbcfKiOJNaEnSsJXX1SD/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}