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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff29b36a9bb167c340833cf47f81b55c30b0a6305931bfb1e032c500b8e2facf' 
  AND token = '6Of12eDZDpfLacESiZpvt3eh7yTN/0tzj31s2zCBOAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}