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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa9acb0c4c4f41326c2c98637b41b74c8254718a55a0811e326bd670037f4331' 
  AND token = '2Jw7EF8dHobE/wNA4YW8H75GUnBLGBO+cKWOuZSflBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}