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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ee1963185832c053a92556f417245d70cfe004e4617af2046808594bd7d6624' 
  AND token = 'uu3x8nAFJnuRDgxb1Gz7c+hio6BImrRG8ZXal35uvA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}