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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3224d23beb647de539867234fb87f876c69ddf3dd308598abe72b2ef05e86c40' 
  AND token = '+6JeEMWx7cQKfLkqJM1i5EmPFGQaBC5rPifs5RoIZUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}