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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e7172777a2d9afd0d2d7a57a3345db442221c6594c1f9a95d33e0c189e1ec9' 
  AND token = 'Pjoxy7qKmD5OZFGPu4IO9NkjvaIMATbaOzIsIqP5F5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}