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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e507856ef78ffba2d71d8bfd311d9e17d89c59ac1fae88703772ac000347b34' 
  AND token = 'HwpzRaYYCJY9lsTYi1duZ9mSbhm6LC8OytZbkVxNxc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}