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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b8311e896d8a0741af227a59da0fe8293671a043881e61e578adb401109e041' 
  AND token = 'lct0/D7ZYyfhG7wvOcQTUIIRD34rxrjiFvnOzhg2M3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}