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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e521c0701da060b59baf68eb94a597073af1e9dfe0c9c8bfa127d27b0023fe7d' 
  AND token = 'Ja/hRpH9Uu2lbqmeGkyBkdhP937E4flC3179XsJGqBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}