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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac33a3570eaf7379a63b1f903c437eac5cff39627c29cf2a08e5b29ceff17e04' 
  AND token = 'M9cjkrcpiA49goxgwwu4AVdPZu2vlt5AQvsvwnb5wMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}