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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b23fa46cfb45e3a45424867ac1b913265143b8d7729ab5e87f189a2e2bcb1261' 
  AND token = 'S4gwBk0ei6vSj30tsMXrMfn9ulkZLx+XcTPsIw7TyvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}