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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5de4dca9ca28746a303fb14a07b4f366b25eaca766d1f5edb723c36dba8b18' 
  AND token = 'TKiDCCxl7fXG/ODmOpOTOO7z36S88EwqCrVm9irjhDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}