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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed462231c6b25632137be9554bcdb494e800118182e583188e3b9db832dd4e5a' 
  AND token = 'fBDeyQ5XxDm9YF9pVqsqTwuez4g2aXq4Ue/KbQMDJ54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}