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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9d3f69c64a3b87e130eec4688c07d5a9d5e87fa711550e371221504a28455d' 
  AND token = 'ZdCxJXWI9v2gRTkMHqLeSWGXCBiUAjPX9us22e8PDAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}