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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b44d5eea39fecb1a2eebdf85c92a1b24d4cbdf7e072b9e0dad43f97dc67560' 
  AND token = 'e45ya9vc6faBLswlrloOy3FfIkPyZa8WmVHkWxZVyc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}